230000002401 inhibitory effect Effects 0.000 claims description 11.238000002441 X-ray diffraction Methods 0.000 claims description 12.239000011230 binding agent Substances 0.000 claims description 18.125000003275 alpha amino acid group Chemical group 0.000 claims description 25.150000001413 amino acids Chemical class 0.000 claims description 48.239000003795 chemical substances by application Substances 0.000 claims description 160.239000003446 ligand Substances 0.000 claims abstract description 41.230000027455 binding Effects 0.000 claims abstract description 77.229920001184 polypeptide Polymers 0.000 claims abstract description 319.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from US76544306P external-priority Application filed by Wyeth Corp filed Critical Wyeth Corp Publication of BRPI0707474A2 publication Critical patent/BRPI0707474A2/pt Links Inventor Lidia Mosyak Brian Dwyer Mark Johnson Xiaotian Zhong Eleonora Presman James M Wilhelm Mark Stahl William Stuart Somers Original Assignee Wyeth Corp Priority date (The priority date is an assumption and is not a legal conclusion. Google Patents BRPI0707474A2 - estrutura da lingo-1Äownload PDF Info Publication number BRPI0707474A2 BRPI0707474A2 BRPI0707474-3A BRPI0707474A BRPI0707474A2 BR PI0707474 A2 BRPI0707474 A2 BR PI0707474A2 BR PI0707474 A BRPI0707474 A BR PI0707474A BR PI0707474 A2 BRPI0707474 A2 BR PI0707474A2 Authority BR Brazil Prior art keywords atom lingo polypeptide agent read Prior art date Application number BRPI0707474-3A Other languages English ( en)
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